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Amanita mushrooms have been historically and culturally significant in rituals and shamanic practices among certain indigenous peoples. In Europe, it is also utilized for its potential medicinal properties, including pain relief, stress reduction, alleviation of anxiety, treatment of skin issues, and aiding those with insomnia. However, it’s important to note that while these uses are documented anecdotally, scientific research on the efficacy and safety of Amanita muscaria for these purposes is limited, and caution should be exercised in its consumption.